Differences Between NMOSD and MS
A blood test for AQP4-IgG can confirm that you have NMOSD. If antibodies against aquaporin-4 (AQP4) are found in your blood, it will confirm you have NMOSD and not MS. AQP4 antibodies are present in up to 80% of people with NMOSD, so testing for this antibody is essential to receiving a diagnosis.
While NMOSD and MS can impact the body in similar ways, there are several factors that differentiate the diseases:
NMOSD
- A single attack can cause disability
- Attacks are usually more severe and can result in permanent disability
- AQP4 antibody positive in a blood test
MS
- Several individual attacks typically cause disability over time
- Attacks are typically less severe and can result in better recovery
- AQP4 antibody negative in a blood test
Partnering with a specialist can help ensure the right diagnosis and disease management.